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    3886-70-2

    Catalog No. EBD2204377

    CAS 3886-70-2

    Name (R)-(+)-1-(1-naphthyl)-ethylamine

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    Basic Information

    Synonyms: (R)-1-(1-naphthyl)ethylamine (R)-(+)-1-(1-naphthyl)-ethylamine R-(+)-1-(1-naphthyl)ethylamine (R)-(+)-1-(1-Naphthyl)ethylamine 1-(naphthalen-1-yl)ethanamine (1R)-1-naphthalen-1-ylethanaminium R-(+)-alpha-(1-Naphthyl)ethylamine (+)-naphthylethylamine (R)-1-(naphthalen-1-yl)ethanamine (R)-(+)-α-(1-Naphthyl)ethylamine (1R)-1-(naphthalen-1-yl)ethan-1-amine (R)-(+)-alpha-(1-Naphthyl)ethylamine

    Molecular Formula: C12H13N

    Molecular Weight: 171.24

    MDL Number: MFCD00064114

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-(+)-1-(1-Naphthyl)ethylamine is a chiral amine compound featuring a naphthalene ring system. It is a valuable chiral building block and resolving agent in organic synthesis, particularly for the preparation of enantiomerically pure compounds. Its primary application is as a chiral auxiliary and resolving agent in pharmaceutical chemistry. The compound is widely used for the kinetic resolution of racemic acids and other chiral molecules, facilitating the production of single-enantiomer active pharmaceutical ingredients (APIs). It serves as a key chiral intermediate in the synthesis of various pharmacologically active agents. The compound is commercially available in high enantiomeric purity and is a standard reagent in asymmetric synthesis methodologies. It requires careful handling as it is corrosive and causes severe skin burns and eye damage.
    Physical Properties

    Boiling Point: 153 °C/11 mmHg(lit.)

    Flash Point: 113 °C

    Density: 1.067 g/mL at 20 °C(lit.)

    Refractivity: n20/D 1.623(lit.)

    Storage: 2-8°C

    Analytical Data

    Appearance: Colorless to light yellow liquid

    mg g kg ml l t