7-(3-Chloropropoxy)-4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxyquinoline-3-carbonitrile is a synthetic quinoline derivative. It is a key intermediate in the synthesis of the potent and selective c-Met kinase inhibitor, Foretinib (GSK1363089, XL880). The compound features a complex heterocyclic core with multiple substituents, including a 3-chloropropoxy chain, a dichloro-methoxyanilino group, and a cyano group, which are crucial for its biological activity. Foretinib, for which this compound serves as a precursor, is an investigational multi-kinase inhibitor targeting c-Met, VEGFR2, and other receptor tyrosine kinases. It has been studied in clinical trials for the treatment of various solid tumors, including gastric cancer, hepatocellular carcinoma, and papillary renal cell carcinoma. The synthesis of this intermediate is a critical step in the production of the active pharmaceutical ingredient (API).