PNP-α-D-glucopyranoside, CAS No. 3767-28-0

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

3767-28-0

Catalog No. EBD2204338

CAS 3767-28-0

Name PNP-α-D-glucopyranoside

Get Quote

Basic Information

Synonyms: para-nitrophenylα-D-glucopyranoside PNP-α-D-glucopyranoside 4-nitrophenylα-D-glucopyranoside 4-Nitrophenylalpha-glucoside 4-Nitrophenylalpha-D-glucopyranoside 4-Nitrophenyl-Alpha-D-Glucopyranoside

Molecular Formula: C12H15NO8

Molecular Weight: 301.25

MDL Number: MFCD00064088

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

4-Nitrophenyl α-D-glucopyranoside is a synthetic glycoside derivative where a 4-nitrophenyl group is linked via an α-glycosidic bond to the anomeric carbon of D-glucose. It is a crystalline solid commonly used as a chromogenic substrate for the assay of α-glucosidase and other glycoside hydrolase enzymes. The primary application of this compound is in biochemical and enzymatic research. The enzymatic hydrolysis of the glycosidic bond by α-glucosidase releases 4-nitrophenol, which is yellow and can be easily quantified spectrophotometrically at around 400 nm under alkaline conditions. This property makes it a standard and convenient tool for measuring enzyme activity, screening enzyme inhibitors (e.g., for diabetes research), and studying enzyme kinetics in vitro. While its main utility is as a diagnostic reagent in life sciences, its well-defined structure also makes it a potential building block in synthetic carbohydrate chemistry for constructing more complex glycoconjugates or probes. It should be handled with standard laboratory precautions, avoiding inhalation and contact with skin and eyes.

Physical Properties

Melting Point: 210-216 °C

Boiling Point: 582.2 °C at 760 mmHg

Flash Point: 305.9 °C

Density: 1.599 g/cm3

Refractivity: 218.5 ° (C=0.5, H2O)

Storage: −20°C

Analytical Data

Appearance: White crystals