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    37535-51-6

    Catalog No. EBD2206198

    CAS 37535-51-6

    Name 3-(2-Pyridyl)-L-alanine

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    Basic Information

    Synonyms: 3-(2-Pyridyl)-L-alanine H-.beta.-(2-Pyridyl)-Ala-OH L-2-Pyridylalanine l-3-(2-pyridyl)-alanine 3-pyridin-2-yl-L-alanine (2R)-2-ammonio-3-pyridin-2-ylpropanoate

    Molecular Formula: C8H10N2O2

    Molecular Weight: 166.18

    MDL Number: MFCD00237827

    Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    3-(2-Pyridyl)-L-alanine is a non-proteinogenic amino acid derivative characterized by an L-alanine backbone with a 2-pyridyl substituent at the β-position. This structure incorporates both a chiral amino acid moiety and a heterocyclic pyridine ring, making it a valuable chiral building block in synthetic and medicinal chemistry. Its primary application is in the field of peptide research and drug discovery. The compound serves as a key intermediate for the synthesis of modified peptides and peptidomimetics. The pyridine ring can act as a metal-chelating group or be used to introduce specific steric and electronic properties into peptide chains, potentially modulating their biological activity, stability, or binding affinity. It is particularly relevant in the design of enzyme inhibitors and receptor ligands. As a specialty amino acid derivative, it is not a commodity chemical but is utilized in research-scale synthesis for developing novel therapeutic candidates and biochemical probes. Handling requires standard precautions for laboratory chemicals.
    Physical Properties

    Boiling Point: 322.4 °C at 760 mmHg

    Flash Point: 148.8 °C

    Density: 1.271 g/cm3

    Storage: Store at 0-5°C

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