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    37386-15-5

    Catalog No. EBD24331

    CAS 37386-15-5

    Name Pyrrolidin-1-ylacetic acid

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    Basic Information

    Synonyms: 1-Pyrrolidineaceticacid Pyrrolidin-1-ylaceticacid PYRROLIDIN-1-YL-ACETICACID Metroprolol 1-[4-(2-methoxyethyl)phenoxy]-3-propan-2-ylamino-propan-2-ol

    Molecular Formula: C6H11NO2

    Molecular Weight: 129.16

    MDL Number: MFCD04114075

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Pyrrolidin-1-ylacetic acid is an organic compound featuring a pyrrolidine ring linked to an acetic acid moiety. This structure makes it a versatile bifunctional building block, containing both a secondary amine and a carboxylic acid functional group. Its primary application is in pharmaceutical research and development as a key intermediate. The compound is notably used in the synthesis of various bioactive molecules and active pharmaceutical ingredients (APIs). For instance, it serves as a crucial precursor in the preparation of certain GABA analogs and other neuroactive compounds. The pyrrolidine ring is a common pharmacophore, and the acetic acid handle allows for further derivatization and conjugation. As a heterocyclic amine derivative, it is a valuable synthon in medicinal chemistry for constructing complex molecular architectures. It is commercially available from suppliers specializing in fine chemicals and pharmaceutical intermediates for research purposes.
    Physical Properties

    Boiling Point: 233.8 oC at 760mmHg

    Flash Point: 95.2 oC

    Density: 1.153g/cm3

    mg g kg ml l t