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    3719-45-7

    Catalog No. EBD37261

    CAS 3719-45-7

    Name 1-Methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid

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    Basic Information

    Synonyms: 1-Methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylicacid 1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylicacid 3-Pyridinecarboxylicacid,1,6-dihydro-1-methyl-6-oxo- 1-methyl-6-pyridone-3-carboxylicacid

    Molecular Formula: C7H7NO3

    Molecular Weight: 153.14

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

    Product Description:
    1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid is a heterocyclic carboxylic acid derivative featuring a pyridone core structure. It serves as a versatile and important building block in medicinal chemistry, particularly for the synthesis of various pharmaceutical compounds. Its primary application is as a key intermediate in the synthesis of quinolone and fluoroquinolone antibiotics. The molecule's structure provides a scaffold that can be further functionalized to introduce the characteristic pharmacophore of these broad-spectrum antimicrobial agents. It is also utilized in the research and development of other bioactive molecules targeting various therapeutic areas. As a bifunctional molecule containing both a carboxylic acid and a heterocyclic ring, it is a valuable synthon in organic synthesis. It can undergo typical carboxylic acid reactions (e.g., amidation, esterification) and participate in modifications on the pyridone ring, making it a useful reagent for constructing complex molecular architectures in drug discovery programs.
    Physical Properties

    Melting Point: 240-245 °C

    Boiling Point: 329.6 °C at 760 mmHg

    Flash Point: 153.2 °C

    Density: 1.382 g/cm3

    Storage: 2-8°C

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