5-Methoxy-1H-benzo[d]imidazole-2-thiol, CAS No. 37052-78-1

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

37052-78-1

Catalog No. EBD20424

CAS 37052-78-1

Name 5-Methoxy-1H-benzo[d]imidazole-2-thiol

Get Quote

Basic Information

Synonyms: 2-Mercapto-5-methoxybenzimidazole 5-Methoxy-2-benzimidazolethiol 5-Methoxy-2-mercaptobenzimidazole 5-Methoxybenzimidazole-2-thiol 5-methyoxy-2-mercaptoBenzimidazole 5-methoxy-1H-benzimidazole-2-thiol 5-methoxybenzimidazolin-2-thione 5-methoxybenzimidazolin-2-mercapto 5-methoxy-1,3-dihydro-benzoimidazole-2-thione 5-Methoxy-1,3-dihydro-benzimidazol-2-thion 1,3-dihydro-5-methoxy-2H-benzimidazole-2-thione Methoxy-2-mercaptobenzimidazole,5- 2-MERCAPTO-5-METHOXY-1H-BENZIMIDAZOLE 5-METHOXY-2-THIOBENZIMIDAZOLE 5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL TIMTEC-BBSBB000219 5-Methoxy-2-mercaplobenzinidazole EsomeprazoleEPimpurities 5-Methoxy-1,

Molecular Formula: C8H8N2OS

Molecular Weight: 180.23

MDL Number: MFCD00134581

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Sulfides and Thioethers

Product Description:

2-Mercapto-5-methoxybenzimidazole is an organic compound featuring a benzimidazole core structure substituted with a thiol (mercapto) group at the 2-position and a methoxy group at the 5-position. It is a solid compound that serves as a versatile heterocyclic building block in organic synthesis. This compound is primarily utilized as a key pharmaceutical intermediate. Its benzimidazole scaffold is a privileged structure in medicinal chemistry, and the presence of the reactive thiol group allows for further functionalization. It is notably used in the synthesis of various pharmacologically active molecules, including certain anthelmintic (anti-parasitic) drugs and other therapeutic agents targeting specific biological pathways. As a bifunctional molecule containing both a heterocyclic amine system and a thiol, it finds applications in coordination chemistry and material science. However, its predominant and most significant use remains within the context of drug discovery and development as a synthetic precursor.

Physical Properties

Melting Point: 261-263 °C(lit.)

Boiling Point: 309.4 °C at 760 mmHg

Flash Point: 140.9 °C

Density: 1.38 g/cm3

Solubility: insoluble