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    369656-57-5

    Catalog No. EBD2206756

    CAS 369656-57-5

    Name 8-Quinolinamine,5,6,7,8-tetrahydro-,(8S)-(9CI)

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    Basic Information

    Synonyms: 8-Quinolinamine,5,6,7,8-tetrahydro-,(8S)- 8-Quinolinamine,5,6,7,8-tetrahydro-,(8S)-(9CI) (8S)-5,6,7,8-Tetrahydro-8-quinolinamine (S)-(+)-8-Amino-5,6,7,8-tetrahydroquinoline (8S)-5,6,7,8-tetrahydroquinolin-8-amine

    Molecular Formula: C9H12N2

    Molecular Weight: 148.2

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (8S)-5,6,7,8-Tetrahydro-8-aminoquinoline is a chiral, heterocyclic organic compound featuring a saturated pyridine ring fused with a partially saturated ring containing an amino group at the stereogenic 8-position. It is a key chiral building block and intermediate in organic synthesis. Its primary and most significant application is in the pharmaceutical industry, where it serves as a crucial intermediate for the synthesis of various active pharmaceutical ingredients (APIs). Notably, it is a key chiral precursor in the production of certain antimalarial drugs and other therapeutic agents that require the specific (S)-configured aminoquinoline scaffold. The compound's structure makes it valuable for constructing complex molecules with biological activity. As a bifunctional molecule containing both an aromatic amine (from the quinoline) and a primary aliphatic amine, it is also utilized in academic and industrial research as a versatile synthetic building block for constructing ligands, catalysts, and more complex heterocyclic systems.
    Physical Properties

    Boiling Point: 277.3 °C at 760 mmHg

    Flash Point: 146 °C

    Density: 1.081 g/cm3

    mg g kg ml l t