(4-(Trifluoromethyl)phenyl)hydrazine, CAS No. 368-90-1

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368-90-1

Catalog No. EBD18272

CAS 368-90-1

Name (4-(Trifluoromethyl)phenyl)hydrazine

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Basic Information

Synonyms: (4-(Trifluoromethyl)phenyl)hydrazine 4-(Trifluoromethyl)-phenylhydrazine 4-(Trifluoromethyl)phenylhydrazine 1-[4-(Trifluoromethyl)phenyl]hydrazine alpha,alpha,alpha-Trifluoro-p-tolylhydrazine 4-(trifluoromethyl)benzoylfluoride p-trifluoromethylphenylhydrazine 4-trifluoromethylphenylhydrazine 1-(4-trifluoromethylphenyl)hydrazine hydrazine,(a,a,a-trifluoro-p-tolyl)-(8ci)

Molecular Formula: C7H7F3N2

Molecular Weight: 176.14

MDL Number: MFCD00042508

Categories: Synthetic Chemistry > Organic Building Blocks > Oximes and Hydrazones Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

4-(Trifluoromethyl)phenylhydrazine is an organic compound featuring a phenyl ring substituted with a trifluoromethyl group and a hydrazine functional group. It is a versatile aromatic hydrazine derivative commonly used as a key building block in organic synthesis. Its primary application is as a precursor for the synthesis of various heterocyclic compounds, particularly pyrazoles and indoles, which are important scaffolds in medicinal chemistry. The hydrazine moiety readily participates in condensation reactions with 1,3-diketones, β-keto esters, or carbonyl compounds to form these privileged structures. Many pharmaceutical agents and agrochemicals contain these heterocycles, making this compound a valuable intermediate in their development. As a specialty synthetic reagent, it is employed in the preparation of dyes, ligands, and functional materials. It should be handled with care as hydrazine derivatives are typically toxic and potentially explosive.

Physical Properties

Melting Point: 63-65 °C(lit.)

Boiling Point: 118-122 °C/17 mmHg(lit.)

Flash Point: 119-121°C/17mm

Density: 1.339 g/cm3

Storage: 2-8°C

Analytical Data

Appearance: Yellow to brownish powder