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    354812-41-2

    Catalog No. EBD29358

    CAS 354812-41-2

    Name 1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid

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    Basic Information

    Synonyms: Moxifloxacin 3-Quinolinecarboxylicacid,1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo- 1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylicacid

    Molecular Formula: C21H24FN3O4

    Molecular Weight: 401.43

    Categories: Medicinal Chemistry > APIs and Their Salts > Anti-infectives Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    This compound, 1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid, is a key chemical entity in the development of novel antibacterial agents. Its core structure is a fluoroquinolone derivative, a well-established class of synthetic broad-spectrum antibiotics. The specific substitution pattern, including the cyclopropyl group at the N-1 position and the diazabicyclononane moiety at the C-7 position, is characteristic of advanced-generation quinolones designed to enhance potency and overcome bacterial resistance. The primary and definitive application of this compound is as a pharmaceutical active ingredient or a direct precursor in the synthesis of antibacterial drugs. It serves as a crucial intermediate for the production of besifloxacin, a fourth-generation fluoroquinolone antibiotic approved for ophthalmic use (e.g., Besivance®). Besifloxacin is specifically indicated for the treatment of bacterial conjunctivitis. The compound's role is integral to constructing the final API, making it both a high-value synthetic building block (a complex heterocyclic intermediate) and fundamentally an anti-infective drug substance.
    Physical Properties

    Boiling Point: 636.382 °C at 760 mmHg

    Flash Point: 338.672 °C

    Density: 1.409 g/cm3

    mg g kg ml l t