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    35051-64-0

    Catalog No. EBD2208412

    CAS 35051-64-0

    Name (R)-amino-cyclohexyl-acetic acid ethyl ester

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    Basic Information

    Synonyms: Hydrochlorid

    Molecular Formula: C10H20ClNO2

    Molecular Weight: 221.72

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-Amino-cyclohexyl-acetic acid ethyl ester is a chiral organic compound featuring an ethyl ester group and a primary amine group attached to a cyclohexylacetic acid backbone. Its molecular formula is C₁₀H₁₉NO₂. This compound is a valuable chiral building block, specifically an α-amino acid ester derivative with a cyclohexyl side chain. The primary application of this compound is as a key chiral intermediate in pharmaceutical synthesis. Its structure makes it a crucial precursor for the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates. It is notably used in the synthesis of certain antiviral agents and other therapeutic molecules where the (R)-configuration of the amino acid moiety is essential for biological activity and target specificity. As a versatile synthon, it is employed in peptide mimetics research and medicinal chemistry to introduce the chiral 1-amino-cyclohexylacetic acid pharmacophore. Its utility stems from the reactivity of both the ester and amine functional groups, allowing for further derivatization and incorporation into more complex molecular architectures.
    Physical Properties
    mg g kg ml l t