Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    34941-91-8

    Catalog No. EBD472398

    CAS 34941-91-8

    Name 2-chloro-4-fluoropyridine

    Get Quote
    Basic Information

    Synonyms: 2-Chloro-4-fluoropyridine 2-Chlor-4-fluorpyridin Pyridine,2-chloro-4-fluoro-

    Molecular Formula: C5H3ClFN

    Molecular Weight: 131.54

    MDL Number: MFCD04039345

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    2-Chloro-4-fluoropyridine is a halogenated heterocyclic compound with the molecular formula C5H3ClFN. It is a versatile organic building block characterized by the presence of both chlorine and fluorine atoms on the pyridine ring, which significantly influences its reactivity and physical properties. This compound is primarily used as a key intermediate in pharmaceutical synthesis. The halogen atoms serve as reactive handles for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) or nucleophilic aromatic substitution, enabling the construction of complex molecules. It is a crucial precursor in the development of various active pharmaceutical ingredients (APIs), particularly those containing a substituted pyridine core. As a bifunctional halogenated pyridine, it is a valuable reagent in medicinal chemistry and organic synthesis research. Its dual halogen substitution pattern allows for selective and sequential modifications, making it a strategic starting material for constructing drug-like scaffolds and exploring structure-activity relationships.
    Physical Properties

    Boiling Point: 140°C

    Flash Point: 54 °C

    Density: 0.997g/cm3

    Safety Information

    Packing Level: III

    Hazard Category: 3

    Transport Codes: 1993C

    mg g kg ml l t