L-THIOPROLINE, CAS No. 34592-47-7

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34592-47-7

Catalog No. EBD2201840

CAS 34592-47-7

Name L-THIOPROLINE

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Basic Information

Synonyms: 4-Thiazolidinecarboxylicacid,(4R)- L(-)-Thiazolidine-4-carboxylicacid Thioproline H-Thz-OH L-Thiazolidine-4-carboxylicacid (4R)-1,3-thiazolidine-4-carboxylicacid L-Thioprolinel L-THIAPROLINE

Molecular Formula: C4H7NO2S

Molecular Weight: 133.17

MDL Number: MFCD00128958

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives Medicinal Chemistry > Pharmaceutical Excipients > Novel and Functional Excipients

Product Description:

L-Thioproline, also known as L-thiazolidine-4-carboxylic acid, is a sulfur-containing amino acid derivative. It is a cyclic analog of L-proline where the pyrrolidine ring's methylene group is replaced by a sulfur atom. This structural modification imparts unique chemical and biological properties distinct from its parent compound. Its primary applications are in the pharmaceutical and life science fields. L-Thioproline has been investigated for its potential biological activities, including as an antioxidant and a modulator of cellular redox status. It has been studied in contexts related to oxidative stress and certain metabolic pathways. In pharmaceutical formulations, it is explored as a functional excipient, particularly for its potential use in stabilizing peptides and proteins or modifying drug delivery profiles due to its specific interactions. As a derivative of a proteinogenic amino acid, it also serves as a specialized building block in peptide chemistry and biochemical research. It is typically handled as a solid and requires standard laboratory safety precautions for handling fine chemicals.

Physical Properties

Melting Point: 190-200 °C (dec.)(lit.)

Boiling Point: 350.3 °C at 760 mmHg

Flash Point: 165.7 °C

Density: 1.38 g/cm3

Solubility: 28.5 g/L (20 ºC)

Refractivity: -200 ° (C=1, 1mol/L NaOH)

Storage: Store at RT.

Safety Information

Packing Level: III

Hazard Category: 6.1

Transport Codes: 2811

Analytical Data

Appearance: solid