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    34368-52-0

    Catalog No. EBD7366

    CAS 34368-52-0

    Name (S)-3-Hydroxypyrrolidine-2-one

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    Basic Information

    Synonyms: (3S)-3-hydroxypyrrolidin-2-one 2-Pyrrolidinone,3-hydroxy-,(3S)- (S)-3-Hydroxypyrrolidin-2-one (S)-3-Hydroxy-Pyrrolidin-2-One (S)-3-Hydroxypyrrolidine-2-one

    Molecular Formula: C4H7NO2

    Molecular Weight: 101.1

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    (S)-3-Hydroxypyrrolidin-2-one is a chiral heterocyclic compound featuring a pyrrolidinone core with a hydroxyl group at the 3-position. It is a versatile building block in organic synthesis, particularly valued for its stereochemistry and functional groups. This compound serves as a crucial intermediate in the pharmaceutical industry. It is notably used in the synthesis of various active pharmaceutical ingredients (APIs), including antiviral drugs and other therapeutics that require a chiral pyrrolidine scaffold. Its structure makes it a valuable precursor for constructing complex molecules with biological activity. Beyond its primary use as a pharmaceutical intermediate, (S)-3-Hydroxypyrrolidin-2-one is also employed as a chiral synthon in asymmetric synthesis and medicinal chemistry research. It is commercially available from chemical suppliers specializing in fine chemicals and chiral building blocks.
    Physical Properties

    Boiling Point: 363.637 °C at 760 mmHg

    Flash Point: 173.722 °C

    Density: 1.292 g/cm3

    mg g kg ml l t