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    3378-71-0

    Catalog No. EBD30083

    CAS 3378-71-0

    Name 2,5-Dimethylpyrrolidine

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    Basic Information

    Synonyms: 2,5-Dimethylpyrrolidine,mixtureofcisandtrans (2R,5S)-2,5-dimethylpyrrolidinium (2R,5R)-2,5-dimethylpyrrolidinium (2S,5S)-2,5-dimethylpyrrolidinium 1,4-Dibenzoylbutane

    Molecular Formula: C6H13N

    Molecular Weight: 99.17

    Categories: Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Catalysts and Ligands > Nitrogen Ligands

    Product Description:
    2,5-Dimethylpyrrolidine is a bicyclic amine compound featuring a pyrrolidine ring with methyl substituents at the 2 and 5 positions. It is a colorless to pale yellow liquid with a characteristic amine odor and is commonly used as a versatile building block and ligand in organic synthesis. Its primary application lies in the field of synthetic chemistry. The compound serves as a chiral diamine ligand in asymmetric catalysis, particularly in metal-catalyzed reactions. It is also employed as a precursor for the synthesis of more complex nitrogen-containing heterocycles and pharmaceutical intermediates. The steric and electronic properties imparted by the methyl groups make it a useful structural motif. As a secondary amine, it can act as a base or a nucleophile in various organic transformations. Handling requires standard precautions for amines, including use in a well-ventilated area and avoidance of contact with skin and eyes.
    Physical Properties

    Boiling Point: 105-106 °C(lit.)

    Flash Point: 7 °C

    Density: 0.81 g/mL at 25 °C(lit.)

    Refractivity: n20/D 1.4299(lit.)

    Safety Information

    Packing Level: II

    Hazard Category: 3

    Transport Codes: 1993BF

    Analytical Data

    Appearance: Clear colorless to pale yellow liquid

    mg g kg ml l t