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    33483-66-8

    Catalog No. EBD2301956

    CAS 33483-66-8

    Name Cyclohexanamine,4-methyl-,hydrochloride

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    Basic Information

    Synonyms: Cyclohexanamine,4-methyl-,hydrochloride Cyclohexanamine,4-methyl-,hydrochloride,cis- Cyclohexylamine,4-methyl-,hydrochloride,cis- cis-4-Methyl-cyclohexylaminehydrochloride

    Molecular Formula: C7H16ClN

    Molecular Weight: 149.66

    MDL Number: MFCD09991703

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Cis-4-Methylcyclohexylamine hydrochloride is an organic compound featuring a cyclohexane ring substituted with an amino group and a methyl group in a cis configuration. It is commonly supplied as a white to off-white crystalline powder or solid. The hydrochloride salt form enhances its stability and handling properties. This compound serves as a valuable chiral building block in pharmaceutical synthesis. Its primary application is as a key intermediate in the production of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. The cis-configured cyclohexylamine scaffold is a privileged structure found in several drug candidates and approved medications, where it contributes to specific binding affinity and pharmacokinetic properties. As a chiral amine, it is used in asymmetric synthesis and medicinal chemistry research to introduce stereochemical complexity. Handling requires standard precautions for amine hydrochlorides, including the use of personal protective equipment to avoid inhalation or contact.
    Physical Properties
    mg g kg ml l t