2'-deoxyguanosine 5'-monophosphate disodium salt, CAS No. 33430-61-4

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33430-61-4

Catalog No. EBD40909

CAS 33430-61-4

Name 2'-deoxyguanosine 5'-monophosphate disodium salt

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Basic Information

Synonyms: 5′-dGMP disodium 2'-Deoxyguanosine-5'-monophosphatedisodiumsalthydrate,99% 2-deoxyguanosine5-monophosphate,disodiumsalt 2-deoxyguanosine5-(disodiumphosphate) 2'-deoxy-5'-guanylicacid disodium2-amino-9-(2-deoxy-5-O-phosphonatopentofuranosyl)-3,9-dihydro-6H-purin-6-one disodium2'-deoxy-5'-O-phosphonatoguanosinehydrate 2'-Deoxyguanosine-5'-monophosphate,disodiumsalt dGMP.Na2 Disodium5'-Dgmp 2'-deoxyguanosine5'-monophosphate 2'-deoxyguanosine5'-monophosphatedisodiumsalt

Molecular Formula: C10H12N5Na2O7P

Molecular Weight: 391.19

MDL Number: MFCD00080331

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Medicinal Chemistry > Drug Impurities and Reference Standards > Drug Metabolite References

Product Description:

2'-Deoxyguanosine 5'-monophosphate disodium salt (dGMP-Na2) is a nucleotide derivative where the ribose sugar of guanosine monophosphate is replaced by 2'-deoxyribose. It is a key monomeric unit in the biosynthesis of DNA. As a disodium salt, it offers improved solubility in aqueous solutions compared to the free acid form, making it suitable for biochemical and molecular biology applications. This compound serves as a crucial substrate in enzymatic reactions, particularly for DNA polymerases during *in vitro* DNA synthesis, sequencing, and PCR. It is also used in the study of nucleotide metabolism and as a reference standard in analytical methods such as HPLC and mass spectrometry for quantifying nucleotides in biological samples. In pharmaceutical research, it can be relevant as a metabolite or impurity reference for nucleoside/nucleotide-based drugs. dGMP-Na2 is a fundamental building block in life science research. It must be stored under appropriate conditions to maintain stability, as nucleotides can be susceptible to degradation by moisture and enzymatic activity.

Physical Properties

Melting Point: >245 °C (dec.)(lit.)

Storage: Store at 0°C

Analytical Data

Appearance: Crystalline