N-ME-VAL-OME hydrochloride, with the CAS number 3339-44-4, is a chemically modified amino acid derivative. Its full chemical name is N-Methyl-L-valine methyl ester hydrochloride. Structurally, it is a valine derivative where the alpha-amino group is methylated (N-methyl) and the carboxylic acid is protected as a methyl ester, supplied as its hydrochloride salt. This modification enhances its lipophilicity and alters its conformational properties compared to the parent amino acid. This compound is primarily utilized as a specialized building block in peptide synthesis and medicinal chemistry. The N-methylation is a key strategy to improve the metabolic stability, membrane permeability, and bioavailability of peptide-based drug candidates. It is commonly employed in the research and development of peptidomimetics and constrained peptides, particularly in the search for novel therapeutics targeting various diseases. As a protected and modified amino acid ester, it serves as a crucial intermediate for introducing the N-methylvaline residue into peptide chains. Its use helps researchers explore structure-activity relationships and develop peptides with enhanced pharmacological profiles. Handling requires standard precautions for laboratory chemicals.