Methyl 5-chloropyrazine-2-carboxylate, CAS No. 33332-25-1

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33332-25-1

Catalog No. EBD44532

CAS 33332-25-1

Name Methyl 5-chloropyrazine-2-carboxylate

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Basic Information

Synonyms: Methyl-5-chloropyrazine-2-carboxylate 5-Chloro-Pyrazine-2-CarboxylicAcidMethylEster Methyl5-Chloropyrazine-2-Carboxylate PyrazinecarboxylicAcid,5-Chloro-,MethylEster 5-Chloro-2-PyrazinecarboxylicAcidMethylEster Methyl-5-Chloro-2-Pyrazinecarboxylate 5-Chloropyrazine-2-Methylcarboxylate Methyl5-Chloropiperazine-2-Carbonate 5-Chloro-2-Methoxycarbonylpyrazine 1-PhenylcyclopropanamineHydrochloride Ethyl3-Aminobicyclo[2.2.1]Hept-5-Ene-2-Carboxylate Ethyl(1R,2S,3R,4S)-3-Aminobicyclo[2.2.1]Hept-5-Ene-2-Carboxylate Ethyl(1R,2S,3R,4S)-3-Aminobicyclo[2.2.1]Hept-5-Ene-2-Carboxyl

Molecular Formula: C6H5ClN2O2

Molecular Weight: 172.57

MDL Number: MFCD01632102

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

Product Description:

Methyl 5-chloropyrazine-2-carboxylate is a heterocyclic compound featuring a pyrazine ring substituted with a chlorine atom at the 5-position and a methyl ester group at the 2-position. Its molecular formula is C6H5ClN2O2, and it appears as a white to light yellow crystalline solid. This compound is primarily utilized as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors and other bioactive molecules targeting central nervous system or oncological pathways. The chlorine atom serves as a versatile handle for further functionalization via cross-coupling reactions, while the ester group allows for subsequent hydrolysis or amidation. Additionally, it is employed as a building block in organic synthesis for constructing more complex heterocyclic structures, making it valuable in medicinal chemistry and agrochemical research.

Physical Properties

Boiling Point: 242.8 °C at 760 mmHg

Flash Point: 100.6 °C

Density: 1.372 g/cm3