Methyl (αS,3S)-α-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-3-pyrrolidinepropanoate, CAS No. 328086-60-8

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328086-60-8

Catalog No. EBD357537

CAS 328086-60-8

Name Methyl (αS,3S)-α-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-3-pyrrolidinepropanoate

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Basic Information

Synonyms: Methyl (αS,3S)-α-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-3-pyrrolidinepropanoate (2S)-2-(tert-butoxycarbonylamino)-3-[(3'S)-2'-oxo-3'-pyrrolidinyl]propanoicacidmethyester 2S-tert-butoxycarbonylamino-3-(2-oxopyrrolidin-3S-yl)-propionicacidmethylester 2-tert-butoxycarbonylamino-3-(2-oxo-pyrrolidin-3-yl)propionicacidmethylester tert-butyl(S)-1-(methoxycarbonyl)-2-((S)-2-oxopyrrolidin-3-yl)ethylcarbamate 2-tert-butoxycarbonylamino-3-(2-oxo-pyrrolidin-3-yl)-propionicacidmethylester (S)-2-(BOc-amino)-3-((S)-2-Oxopyrrolidine-3-yl)Propanoic Acid Methyl Ester

Molecular Formula: C13H22N2O5

Molecular Weight: 286.33

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

Methyl (ж┴S,3S)-ж┴-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-3-pyrrolidinepropanoate is a chiral, Boc-protected amino acid derivative featuring a 2-oxo-3-pyrrolidine (a lactam) ring. Its structure combines a tert-butoxycarbonyl (Boc) protected amine, a methyl ester, and a stereochemically defined pyrrolidinone scaffold, making it a key synthetic intermediate. This compound is primarily utilized as a building block in medicinal chemistry for the synthesis of small-molecule drug candidates, particularly those targeting neurological, metabolic, or inflammatory pathways. The Boc group allows for selective deprotection under acidic conditions, while the lactam moiety serves as a conformationally constrained core, often employed to improve metabolic stability and binding affinity in drug design. It is also a valuable fragment for constructing peptide mimetics and heterocyclic libraries in early-stage drug discovery.

Physical Properties