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    32559-18-5

    Catalog No. EBD2208172

    CAS 32559-18-5

    Name 2-piperidine-carboxylic acid methyl ester hydrochloride

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    Basic Information

    Synonyms: methyl2-piperidinecarboxylatehydrochloride 2-piperidine-carboxylicacidmethylesterhydrochloride methylpipecolinatehydrochloride methylpiperidine-2-carboxylatehydrochloride(1:1)

    Molecular Formula: C7H14ClNO2

    Molecular Weight: 179.64

    MDL Number: MFCD00192316

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Methyl 2-piperidinecarboxylate hydrochloride is a hydrochloride salt of a piperidine carboxylic acid ester. It is a white to off-white crystalline powder. The compound features a piperidine ring, a common nitrogen-containing heterocycle, and a methyl ester group, making it a versatile chiral building block. This compound is primarily used as a key pharmaceutical intermediate. Its structure serves as a crucial scaffold in the synthesis of various bioactive molecules and active pharmaceutical ingredients (APIs). It is particularly valuable in medicinal chemistry for constructing complex molecules that target the central nervous system and other therapeutic areas, leveraging the piperidine moiety's prevalence in drug design. As a protected form of pipecolic acid (a non-proteinogenic amino acid), it is a valuable chiral synthon in organic synthesis. It is employed in the preparation of peptides, peptidomimetics, and other fine chemicals where the stereochemistry of the piperidine ring is important.
    Physical Properties

    Melting Point: 205 °C (dec.)(lit.)

    Boiling Point: 235.3 °C at 760 mmHg

    Flash Point: 96.1 °C

    mg g kg ml l t