Iodobenzene diacetate, also known as (diacetoxyiodo)benzene (PIDA), is a hypervalent iodine(III) reagent. It features a central iodine atom bonded to a phenyl group and two acetate ligands, giving it a distinctive T-shaped molecular geometry. This stable, crystalline solid is a versatile and mild oxidizing agent widely used in organic synthesis. Its primary application is as a selective oxidant in various transformations, including the oxidation of alcohols to carbonyl compounds, the dehydrogenation of phenols, and the formation of carbon-heteroatom bonds. PIDA is particularly valued in the synthesis of heterocycles and natural products, often serving as a safer and more environmentally friendly alternative to heavy metal-based oxidants like lead tetraacetate. It is also employed in Hofmann rearrangement and other oxidative rearrangements. As a hypervalent iodine compound, PIDA is a key reagent in modern synthetic chemistry due to its high reactivity, ease of handling, and predictable selectivity. It is typically stored under cool, dry conditions to prevent decomposition. While not a pharmaceutical or material itself, its role as a fundamental building block for creating complex molecular structures makes it an indispensable tool in both academic research and industrial process development.