methyl 2-acetamido-3-[(2-acetamido-3-methoxy-3-oxopropyl)disulfanyl]propanoate, CAS No. 32381-28-5

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32381-28-5

Catalog No. EBD181297

CAS 32381-28-5

Name methyl 2-acetamido-3-[(2-acetamido-3-methoxy-3-oxopropyl)disulfanyl]propanoate

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Basic Information

Synonyms: methyl2-acetamido-3-[(2-acetamido-3-methoxy-3-oxo-propyl)disulfanyl]propanoate methyl2-acetamido-3-[(2-acetamido-3-methoxy-3-oxopropyl)disulfanyl]propanoate (Ac-Cys-OMe)2(Disulfidebond) dimethylN,N'-diacetylcystinate dimethylN,N'-diacetyl-L-cystinate N-Acetyl-L-CysteineMethylEster

Molecular Formula: C12H20N2O6S2

Molecular Weight: 352.43

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

Product Description:

Acetyl-L-cystine dimethyl ester is a derivative of the amino acid L-cysteine, specifically the dimethyl ester of N-acetyl-L-cystine. It features a disulfide bridge and protected functional groups (acetylated amine and esterified carboxylates), making it a stable and versatile building block. This compound is primarily used in peptide synthesis and pharmaceutical research. The protected form allows for selective deprotection and incorporation into peptide chains, particularly useful for introducing the cystine moiety, which is crucial for forming disulfide bonds that stabilize the three-dimensional structure of peptides and proteins. It serves as a key intermediate in the synthesis of glutathione analogs and other biologically active peptides. Its application is centered on life science research and the development of peptide-based therapeutics, where controlled introduction of disulfide linkages is essential for biological activity and stability.

Physical Properties

Melting Point: 77-81 °C

Boiling Point: 584.5°Cat760mmHg

Flash Point: 307.3°C

Density: 1.285g/cm3