6-Methylnicotinicacid, CAS No. 3222-47-7

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3222-47-7

Catalog No. EBD46971

CAS 3222-47-7

Name 6-Methylnicotinicacid

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Basic Information

Synonyms: 6-Methylnicotinicacid 6-Methylpyridine-3-carboxylicacid 6-methylpyridine-3-carboxylate

Molecular Formula: C7H7NO2

Molecular Weight: 137.14

MDL Number: MFCD00006341

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

Product Description:

6-Methylnicotinic acid is an organic compound featuring a pyridine ring substituted with a methyl group at the 6-position and a carboxylic acid group at the 3-position. It serves as a versatile and important heterocyclic building block in organic synthesis and pharmaceutical research. Its primary application is as a key intermediate in the synthesis of various pharmaceutical compounds. Notably, it is a crucial precursor in the production of Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor used for the treatment of type 2 diabetes. The molecule's structure allows for further functionalization, making it valuable for constructing more complex heterocyclic systems relevant to medicinal chemistry. Beyond its specific pharmaceutical use, 6-methylnicotinic acid is also employed as a general synthetic intermediate in research settings for the preparation of ligands, functional materials, and other bioactive molecules.

Physical Properties

Melting Point: 210-213 °C(lit.)

Boiling Point: 296.2 °C at 760 mmHg

Flash Point: 132.9 °C

Density: 1.23 g/cm3

Analytical Data

Appearance: White crystalline