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    3215-64-3

    Catalog No. EBD4492

    CAS 3215-64-3

    Name 2,6-Dichlorophenylacetonitrile

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    Basic Information

    Synonyms: 2,6-Dichlorobenzylcyanide 2,6-Dichlorobenzylacetonitrile 2,6-Dichlorophenylacetonitrile 2,6-Dichlorophenylaceticacidnitrile Acetonitrile,(2,6-dichlorophenyl)

    Molecular Formula: C8H5Cl2N

    Molecular Weight: 186.04

    MDL Number: MFCD00001901

    Categories: Synthetic Chemistry > Organic Building Blocks > Cyano Compounds Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    2,6-Dichlorobenzyl cyanide is an organic compound featuring a benzene ring substituted with two chlorine atoms at the ortho positions relative to a cyanomethyl group. It is a versatile bifunctional synthetic building block, combining the reactivity of an aryl halide and a nitrile group. Its primary application is in chemical synthesis as a key intermediate. The aromatic chlorine atoms are susceptible to nucleophilic aromatic substitution or metal-catalyzed cross-coupling reactions, allowing for the introduction of various functional groups. The nitrile group can be hydrolyzed to a carboxylic acid, reduced to an amine, or serve as a precursor to heterocycles like tetrazoles. This dual functionality makes it valuable for constructing more complex molecules, particularly in pharmaceutical and agrochemical research for the synthesis of substituted benzylamines, benzoic acids, and fused ring systems. The compound is typically a solid at room temperature and requires careful handling due to the potential toxicity associated with both cyanide and aromatic halide functionalities. It should be used in well-ventilated areas with appropriate personal protective equipment.
    Physical Properties

    Melting Point: 73-75 °C(lit.)

    Boiling Point: 286.9 °C at 760 mmHg

    Flash Point: 124 °C

    Density: 1.333 g/cm3

    Analytical Data

    Appearance: White to light yellow crystalline powder

    mg g kg ml l t