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    31981-44-9

    Catalog No. EBD2201790

    CAS 31981-44-9

    Name Gestonorone Acetate

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    Basic Information

    Synonyms: 19-Norpregn-4-ene-3,20-dione,17-(acetyloxy)- GestonoroneAcetate 17-hydroxy-19-norpregn-4-ene-3,20-dione17-acetate 17alpha-Hydroxy-19-norprogesterone-17alphaacetate 17alpha-Hydroxy-19norprogesterone-17alphaacetate 19-Nor-17alpha-hydroxyprogesteroneacetate (17alpha)-17-acetyl-3-oxoestr-4-en-17-ylacetate Gestonoronacetat

    Molecular Formula: C22H30O4

    Molecular Weight: 358.47

    Categories: Medicinal Chemistry > APIs and Their Salts > Endocrine & Metabolic Drugs Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

    Product Description:
    19-Nor-4-androstene-3,17-dione 17-acetate is a synthetic steroid derivative. It is structurally characterized as a 19-norandrostane bearing a 3-keto, Δ4-ene, and a 17β-acetoxy group. This compound serves as a key chiral intermediate in the synthesis of various steroidal active pharmaceutical ingredients (APIs). Its primary industrial application is in the production of anabolic-androgenic steroids and other related therapeutic agents. It is a crucial precursor in the synthesis of Nandrolone (19-nortestosterone) and its esters, such as Nandrolone decanoate. These APIs are used clinically for the treatment of conditions like osteoporosis, anemia associated with renal insufficiency, and as part of certain hormone replacement therapies, falling under the category of endocrine and metabolic drugs. The 17-acetate group in this molecule is a common protecting group or a handle for further chemical modifications, making it a valuable and specific building block in steroid chemistry. Its handling requires appropriate safety precautions typical for fine chemical intermediates.
    Physical Properties

    Melting Point: 228-230 °C

    Boiling Point: 490.2 °C at 760 mmHg

    Flash Point: 212.8 °C

    Density: 1.16 g/cm3

    mg g kg ml l t