6-methoxy-1H-indole, CAS No. 3189-13-7

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3189-13-7

Catalog No. EBD2204191

CAS 3189-13-7

Name 6-methoxy-1H-indole

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Basic Information

Synonyms: 6-methoxyindole 6-Methoxylindole 6-Methoxy-1H-indole 6-Methoxy-indol 6-methoxy-indole indole,6-methoxy- 1h-indole,6-methoxy-

Molecular Formula: C9H9NO

Molecular Weight: 147.17

MDL Number: MFCD00022780

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

6-Methoxyindole is an organic compound featuring an indole ring system substituted with a methoxy group at the 6-position. It is a solid at room temperature and serves as a versatile heterocyclic building block in organic synthesis. Its primary and most significant application is in the pharmaceutical industry as a key intermediate for the synthesis of various bioactive molecules. Notably, it is a crucial precursor in the production of serotonin receptor agonists and antagonists, as well as other central nervous system (CNS) active drugs. The indole scaffold is a privileged structure in medicinal chemistry, and 6-methoxyindole provides a specific substitution pattern for drug discovery programs targeting neurological and psychiatric disorders. As a functionalized indole derivative containing both an aromatic amine and an electron-donating methoxy group, it is also a valuable starting material in academic and industrial research for constructing more complex heterocyclic systems and fine chemicals.

Physical Properties

Melting Point: 90-92 °C(lit.)

Boiling Point: 105°C 0,2mm

Flash Point: 105°C/0.2mm

Density: 1.169 g/cm3

Storage: Keep Cold