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    31570-97-5

    Catalog No. EBD2224204

    CAS 31570-97-5

    Name 5-Hydroxyquinolin-2(1H)-one

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    Basic Information

    Synonyms: 5-Hydroxyquinolin-2(1H)-one

    Molecular Formula: C9H7NO2

    Molecular Weight: 161.16

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Other Biochemicals and Life Science Reagents

    Product Description:
    5-Hydroxy-2(1H)-quinolinone is a heterocyclic organic compound featuring a quinolinone core structure substituted with a hydroxyl group at the 5-position. It serves as a versatile and important synthetic building block in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmacologically active compounds. Notably, it is a crucial precursor in the production of certain quinolone and fluoroquinolone antibiotics, such as ciprofloxacin and norfloxacin, where it forms the core heterocyclic scaffold. The molecule's structure allows for further functionalization, making it valuable for constructing libraries of compounds for biological screening. Beyond its role in antibiotic synthesis, derivatives of 5-hydroxy-2(1H)-quinolinone have been investigated for other biological activities, including potential use as kinase inhibitors or in materials science. It is typically handled as a research chemical in laboratory settings.
    Physical Properties

    Boiling Point: 402.4 °C at 760 mmHg

    Flash Point: 197.2 °C

    Density: 1.337 g/cm3

    mg g kg ml l t