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    314741-39-4

    Catalog No. EBD12546

    CAS 314741-39-4

    Name (S)-1-N-Boc-piperazine-3-carboxylic acid methyl ester

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    Basic Information

    Synonyms: (S)-4-N-Boc-piperazine-2-carboxylicacidmethylester (S)-1-N-Boc-piperazine-3-carboxylicacidmethylester 1-tert-butyl3-methyl(3S)-piperazine-1,3-dicarboxylate 1-tert-butyl3-methyl(3R)-piperazine-1,3-dicarboxylate (S)-4-Boc-piperazine-2-carboxylicacidmethylester

    Molecular Formula: C11H20N2O4

    Molecular Weight: 244.29

    MDL Number: MFCD04115326

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-1-N-Boc-piperazine-3-carboxylic acid methyl ester is a chiral piperazine derivative featuring both a tert-butoxycarbonyl (Boc) protecting group on the nitrogen and a methyl ester functionality. This specific stereochemistry and functional group combination make it a valuable, well-defined building block in synthetic organic chemistry. Its primary application is as a key chiral intermediate in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). The Boc-protected amine and ester group provide orthogonal handles for further chemical modifications, allowing for the efficient construction of complex molecules containing the piperazine scaffold. Piperazine rings are prevalent in numerous drugs targeting central nervous system disorders, infectious diseases, and other therapeutic areas. This compound is commercially available from suppliers specializing in fine chemicals and advanced intermediates for medicinal chemistry. It is typically handled under standard laboratory conditions, and its stability and defined purity make it suitable for use in multi-step synthetic routes aimed at drug discovery and development.
    Physical Properties

    Boiling Point: 321.3 °C at 760 mmHg

    Flash Point: 148.1 °C

    Density: 1.118 g/cm3

    mg g kg ml l t