3-Bromobenzaldehyde, CAS No. 3132-99-8

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3132-99-8

Catalog No. EBD29342

CAS 3132-99-8

Name 3-Bromobenzaldehyde

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Basic Information

Synonyms: m-bromobenzaldehyde 3-romobenzaldehyde 3-Bromobenzaldehyde

Molecular Formula: C7H5BrO

Molecular Weight: 185.02

MDL Number: MFCD00003345

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones

Product Description:

3-Bromobenzaldehyde is an aromatic aldehyde featuring a bromine atom at the meta position of the benzene ring. It is a key synthetic building block widely used in organic synthesis, particularly in cross-coupling reactions such as Suzuki, Heck, and Sonogashira couplings, where the bromine serves as a reactive handle. As a versatile intermediate, it is extensively employed in the pharmaceutical industry for the construction of small-molecule drug fragments and active pharmaceutical ingredients (APIs). Its aldehyde group allows for further functionalization via reductive amination, Grignard addition, or condensation reactions, making it valuable in medicinal chemistry for developing candidates targeting various therapeutic areas. Additionally, it serves as a precursor in the synthesis of agrochemicals and fine chemicals.

Physical Properties

Melting Point: 18-21 °C(lit.)

Boiling Point: 233-236 °C(lit.)

Flash Point: 96 °C

Density: 1.587 g/mL at 25 °C(lit.)

Solubility: DECOMPOSES

Refractivity: n20/D 1.593(lit.)