5-bromopicolinaldehyde, CAS No. 31181-90-5

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31181-90-5

Catalog No. EBD489736

CAS 31181-90-5

Name 5-bromopicolinaldehyde

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Basic Information

Synonyms: 5-bromopicolinaldehyde 5-BROMO-2-PYRIDINECARBOXALDEHYDE 5-BROMO-2-FORMYLPYRIDINE 5-BROMO-PYRIDINE-2-CARBALDEHYDE 2-Formyl-5-Bromopyridine 5-Bromopyridine-2-carbaldehyde 5-BROMO-2-PYRIDINECARBALDEHYDE 5-bromo-2-picolinaldehyde 5-bromo-2-formylpyridine,5-bromo-2-picolinaldehyde

Molecular Formula: C6H4BrNO

Molecular Weight: 186.01

MDL Number: MFCD04112535

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones

Product Description:

5-Bromo-2-pyridinecarboxaldehyde is an important heterocyclic organic building block. It features both a bromine atom and an aldehyde group on a pyridine ring, making it a versatile intermediate for various coupling and condensation reactions. This compound is widely used in organic synthesis, particularly in the construction of more complex heterocyclic systems and functionalized pyridine derivatives. It serves as a key precursor in the synthesis of pharmaceuticals, agrochemicals, and materials science products. The bromine atom is amenable to cross-coupling reactions (e.g., Suzuki, Stille), while the aldehyde group can undergo nucleophilic addition, reductive amination, or serve as a handle for further functionalization. Due to its bifunctional nature, it is a valuable reagent for medicinal chemistry research and the development of ligands for catalysis. It should be handled with care in a well-ventilated area, as it may cause skin and eye irritation.

Physical Properties

Melting Point: 91-96 °C

Boiling Point: 237.707 °C at 760 mmHg

Flash Point: 97.562 °C

Density: 1.683 g/cm3

Storage: 2-8°C