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    3082-96-0

    Catalog No. EBD2204859

    CAS 3082-96-0

    Name methyl 1,2,3,4-tetra-O-acetyl-α/β-D-glucopyranosiduronate

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    Basic Information

    Synonyms: 1,2,3,4-Tetra-O-acetyl-D-glucopyranuronsaeure-methylester methyl1,2,3,4-tetra-O-acetyl-α/β-D-glucopyranosiduronate D-Glucopyranuronicacid,methylester,1,2,3,4-tetraacetate D-Glucopyranuronicacid,methylester,tetraacetate(9CI) Glucopyranuronicacid,methylester,tetraacetate(6CI,7CI) Glucopyranuronicacid,methylester,tetraacetate,D-(8CI)

    Molecular Formula: C15H20O11

    Molecular Weight: 376.31

    Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks

    Product Description:
    Methyl 1,2,3,4-tetra-O-acetyl-α/β-D-glucopyranosiduronate is a fully acetylated methyl ester derivative of D-glucuronic acid. It serves as a crucial protected intermediate in carbohydrate and medicinal chemistry. The compound features acetyl groups protecting all hydroxyl functionalities and a methyl ester at the carboxylic acid position, making it a stable and versatile building block. Its primary application is in the synthesis of glucuronide conjugates, which are major metabolites of many drugs and xenobiotics. This makes it an essential reagent for preparing drug metabolites, prodrugs, and molecular probes used in pharmacokinetic and metabolic studies. It is also a key starting material for synthesizing complex oligosaccharides, glycoconjugates, and glycomimetics with potential therapeutic applications. The product is typically supplied as a mixture of anomers (α and β). As a protected sugar derivative, it facilitates selective glycosylation reactions and further functionalization at specific positions after deprotection, which is vital for constructing structurally defined bioactive molecules.
    Physical Properties
    mg g kg ml l t