1-cyclobutylethanone, CAS No. 3019-25-8

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3019-25-8

Catalog No. EBD38351

CAS 3019-25-8

Name 1-cyclobutylethanone

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Basic Information

Synonyms: 1-cyclobutylethanone cyclobutylmethylketone Acetylcyclobutane cyclobutane,acetyl- 1-cyclobutylethan-1-one methylcyclobutylketone

Molecular Formula: C6H10O

Molecular Weight: 98.14

MDL Number: MFCD00037148

Categories: Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

Cyclobutyl methyl ketone is an organic compound featuring a cyclobutane ring directly attached to a carbonyl group. It is a clear, colorless to pale yellow liquid with a characteristic ketone odor. This compound serves as a versatile and valuable building block in organic synthesis, particularly in medicinal chemistry. Its primary application lies in pharmaceutical research and development, where it is used as a key intermediate for constructing more complex molecules. The strained four-membered cyclobutyl ring is of significant interest as it can impart unique conformational and metabolic properties to drug candidates. It is frequently employed in the synthesis of novel chemical entities targeting various therapeutic areas. As a fundamental synthetic intermediate, it is also utilized in materials science and fragrance chemistry. Handling requires standard precautions for ketones, including use in well-ventilated areas and avoidance of ignition sources due to its flammability.

Physical Properties

Boiling Point: 137-139 °C/754 mmHg(lit.)

Flash Point: 29 °C

Density: 0.902 g/mL at 25 °C(lit.)

Refractivity: n20/D 1.432(lit.)

Safety Information

Packing Level: III

Hazard Category: 3

Transport Codes: 1224C

Analytical Data

Appearance: clear colorless to yellow-greenish liquid