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    298690-89-8

    Catalog No. EBD10631

    CAS 298690-89-8

    Name (R)-2-(4-Fluorophenyl)pyrrolidine

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    Basic Information

    Synonyms: (R)-2-(4-fluorophenyl)pyrrolidine (2R)-2-(4-Fluorophenyl)pyrrolidine pyrrolidine,2-(4-fluorophenyl)-,(2R)-

    Molecular Formula: C10H12FN

    Molecular Weight: 165.21

    MDL Number: MFCD06761855

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-2-(4-Fluorophenyl)pyrrolidine is a chiral, fluorinated heterocyclic amine. It features a pyrrolidine ring substituted at the 2-position with a 4-fluorophenyl group, and the stereocenter at this position is in the (R)-configuration. This specific stereochemistry is crucial for its intended applications. This compound is primarily utilized as a key chiral intermediate or building block in pharmaceutical research and development. Its structure, combining a basic amine functionality within a constrained pyrrolidine ring and a fluorinated aromatic moiety, makes it a valuable scaffold for constructing bioactive molecules. It is notably referenced in the synthesis of potential drug candidates targeting the central nervous system and other therapeutic areas, where the (R)-enantiomer is often required for optimal biological activity. As a secondary classification, it serves as a specialized organic synthesis building block, specifically within the categories of amines and heterocyclic compounds. Its use extends to asymmetric synthesis and medicinal chemistry projects where introducing a chiral, fluorinated pyrrolidine unit is desired.
    Physical Properties

    Boiling Point: 235.5 °C at 760 mmHg

    Flash Point: 96.3 °C

    Density: 1.078 g/cm3

    mg g kg ml l t