(2-Amino-5-chlorophenyl)(2-chlorophenyl)methanone, CAS No. 2958-36-3

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2958-36-3

Catalog No. EBD7217

CAS 2958-36-3

Name (2-Amino-5-chlorophenyl)(2-chlorophenyl)methanone

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Basic Information

Synonyms: 2-Amino-2',5-dichlorobenzophenone 2-Amino-2,5-DichloroBenzophenone 2-amino-5-chlorophenyl)(2-chlorophenyl)-methanon 2-amino-2',5-dichloro-benzophenon 2-amino-5,2'-dichlor-benzophenone Benzophenone,2-amino-2',5-dichloro- TIMTEC-BBSBB003068 2-AMINO-5,2'-DICHLOROBENZOPHENONE (2-AMINO-5-CHLOROPHENYL)(2-CHLOROPHENYL)METHANONE 2'-AMINO-5'-CHLOROBENZOYL-2-CHLOROBENZENE 2-(3-Amino-4-Chlorobenyzoyl)BenzoicAcid 2-Amino-5,2-dichlorobenzophenone 2-amino-5-chlorophenyl)(2

Molecular Formula: C13H9Cl2NO

Molecular Weight: 266.12

MDL Number: MFCD00007840

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

(2-Amino-5-chlorophenyl)(2-chlorophenyl)methanone is an aromatic ketone derivative featuring both amino and chloro substituents on its phenyl rings. It is a yellow to brown crystalline powder with a molecular formula of C13H9Cl2NO. This compound is primarily utilized as a key pharmaceutical intermediate. Its most notable application is in the synthesis of benzodiazepine derivatives, a major class of psychoactive drugs. Specifically, it serves as a crucial building block in the production of diazepam and other related anxiolytic and sedative agents. The molecule's structure, containing a reactive amino group adjacent to a carbonyl, allows for cyclization reactions to form the characteristic diazepine ring system. As a bifunctional synthon containing both an amine and a ketone, it also finds use in broader organic synthesis for constructing more complex molecules. Standard safety precautions for handling fine chemicals should be observed, including the use of personal protective equipment due to its potential irritant properties.

Physical Properties

Melting Point: 87-89 °C(lit.)

Boiling Point: 453.6 °C at 760 mmHg

Flash Point: 228.1 °C

Density: 1.373 g/cm3

Solubility: methanol: soluble