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    2924-16-5

    Catalog No. EBD24021

    CAS 2924-16-5

    Name 3-Fluorophenylhydrazine hydrochloride

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    Basic Information

    Synonyms: (3-fluorophenyl)hydrazine (3-Fluorophenyl)hydrazinemonohydrochloride 3-Fluorophenylhydrazinehydrochloride 1-(3-fluorophenyl)hydrazinehydrochloride

    Molecular Formula: C6H8ClFN2

    Molecular Weight: 162.59

    MDL Number: MFCD00012934

    Categories: Synthetic Chemistry > Organic Building Blocks > Oximes and Hydrazones Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    3-Fluorophenylhydrazine hydrochloride is an organic compound featuring a phenyl ring substituted with a fluorine atom at the meta position and a hydrazine group, which is protonated as a hydrochloride salt. This structure combines the properties of an aryl fluoride and a hydrazine derivative. Its primary application is as a versatile building block in organic synthesis. The hydrazine moiety is a key functional group for the construction of various nitrogen-containing heterocycles, such as pyrazoles and indoles, through reactions like condensation with 1,3-dicarbonyl compounds or via Fischer indole synthesis. The fluorine substituent can influence the electronic properties and metabolic stability of the final molecules. Consequently, it serves as a valuable intermediate in the research and development of pharmaceuticals and agrochemicals. The compound is typically handled as a solid and requires storage under inert conditions due to the sensitivity of the hydrazine group. It is commercially available for use in laboratory-scale synthesis.
    Physical Properties

    Melting Point: 268 °C (dec.)(lit.)

    Boiling Point: 226.7 °C at 760 mmHg

    Flash Point: 90.9 °C

    Analytical Data

    Appearance: white to light yellow crystal powder

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