2-(Aminooxy)acetic acid hydrochloride(2:1), CAS No. 2921-14-4

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2921-14-4

Catalog No. EBD42046

CAS 2921-14-4

Name 2-(Aminooxy)acetic acid hydrochloride(2:1)

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Basic Information

Synonyms: O-(Carboxymethyl)hydroxylaminehemihydrochloride (aminooxy)acetate (aminooxy)aceticacid (carboxymethoxy)ammoniumchloride(aminooxy)aceticacid(1:1:1) (aminooxy)aceticacidhydrochloride (aminooxy)aceticacidhydrochloride(1:1) 2-(Aminooxy)aceticacidhydrochloride(2:1) Carboxymethoxylaminehemihydrochloride (Aminooxy)aceticacidhemihydrochloride

Molecular Formula: C4H11ClN2O6

Molecular Weight: 218.59

MDL Number: MFCD01671589

Categories: Synthetic Chemistry > Basic Synthetic Reagents > Other Basic Synthetic Reagents Synthetic Chemistry > Organic Building Blocks > Oximes and Hydrazones

Product Description:

Carboxymethoxylamine hemihydrochloride is a white to off-white crystalline powder with the molecular formula C2H5NO3·½HCl. It is a bifunctional reagent containing both a hydroxylamine group and a carboxylic acid group, making it a versatile building block in organic synthesis. Its primary application is as a key reagent for the preparation of oximes and hydroxamic acids. The hydroxylamine moiety readily reacts with aldehydes and ketones to form oximes, which are valuable intermediates in various synthetic pathways, including the protection of carbonyl groups and the synthesis of heterocycles. The carboxylic acid group allows for further functionalization or conjugation. This compound is widely used in research and development for the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is hygroscopic and should be stored in a cool, dry place. As with many hydroxylamine derivatives, it requires careful handling due to potential irritant properties.

Physical Properties

Melting Point: 156 °C (dec.)(lit.)

Boiling Point: 326.7 °C at 760 mmHg

Flash Point: 151.4 °C

Solubility: decomposes

Storage: 2-8°C

Analytical Data

Appearance: white to off-white crystalline powder or crystals