DL-3-(3,4-Dimethoxyphenyl)-2-methyl-2-hydrazine propionic acid, CAS No. 28860-96-0

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28860-96-0

Catalog No. EBD41641

CAS 28860-96-0

Name DL-3-(3,4-Dimethoxyphenyl)-2-methyl-2-hydrazine propionic acid

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Basic Information

Synonyms: DL-3-(3,4-Dimethoxyphenyl)-2-methyl-2-diazanylpropionicacid 3-(3,4-dimethoxyphenyl)-2-hydrazinyl-2-methylpropanoicacid DL-3-(3,4-Dimethoxyphenyl)-2-methyl-2-hydrazinepropionicacid

Molecular Formula: C12H18N2O4

Molecular Weight: 254.28

MDL Number: MFCD08063342

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates Medicinal Chemistry > APIs and Their Salts > Cardiovascular Drugs

Product Description:

DL-3-(3,4-Dimethoxyphenyl)-2-methyl-2-hydrazine propionic acid is a key synthetic intermediate in the production of the antihypertensive drug methyldopa. Methyldopa is a centrally acting alpha-2 adrenergic agonist used for the management of high blood pressure, particularly during pregnancy. This compound serves as a crucial precursor in the synthetic pathway of methyldopa. The molecule features a hydrazine functional group attached to a substituted propionic acid core with a 3,4-dimethoxyphenyl ring. Its primary industrial and research significance lies in its role as a building block for the final active pharmaceutical ingredient (API). As an intermediate, it is handled under controlled conditions in pharmaceutical manufacturing settings. Its classification is directly tied to its application in cardiovascular drug synthesis, rather than as a general-purpose chemical reagent.

Physical Properties

Boiling Point: 450.953 °C at 760 mmHg

Flash Point: 226.529 °C

Density: 1.208g/cm3