luteolin-8-C-glucoside, CAS No. 28608-75-5

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28608-75-5

Catalog No. EBD933268

CAS 28608-75-5

Name luteolin-8-C-glucoside

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Basic Information

Synonyms: 2-(3,4-Dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one (1S)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol 8-C-2-D-glucopyranosyl-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one luteolin8-C-2-D-glucopyranoside luteolin-8-C-2-D-glucopyranoside orientin7-O-2-D-glucopyranoside luteolin-8-C-glucoside 3',4',5,7-tetrahydroxyflavone8-glucoside

Molecular Formula: C21H20O11

Molecular Weight: 448.38

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Phytochemicals and Natural Products Medicinal Chemistry > APIs and Their Salts > Cardiovascular Drugs

Product Description:

Orientin, also known as homoorientin or luteolin-8-C-glucoside, is a natural flavonoid C-glycoside. It is a yellow crystalline powder with the molecular formula C21H20O11. This compound is widely distributed in various medicinal plants, such as *Trollius chinensis*, *Passiflora incarnata*, and bamboo leaves. Its primary significance lies in its broad spectrum of pharmacological activities. Orientin exhibits potent antioxidant, anti-inflammatory, and cardioprotective effects. Research indicates it can protect against myocardial ischemia-reperfusion injury, reduce atherosclerosis, and improve endothelial function. It also shows neuroprotective, antiviral, and anticancer potential. Due to these properties, it is extensively studied as a potential active pharmaceutical ingredient (API) or lead compound for cardiovascular and metabolic diseases. As a natural product, orientin is a key marker compound for the quality control of several herbal medicines. Its safety profile is generally favorable, but comprehensive toxicological data for therapeutic use is still under investigation. Current applications are primarily in research, dietary supplements, and traditional medicine formulations.

Physical Properties

Color: yellow

Melting Point: 260-285 °C

Boiling Point: 816.1 °C at 760 mmHg

Flash Point: 289.1 °C

Density: 1.759 g/cm3

Solubility: 1

Analytical Data

Appearance: yellow powder