Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    2859-67-8

    Catalog No. EBD77136

    CAS 2859-67-8

    Name 3-pyridin-3-ylpropan-1-ol

    Get Quote
    Basic Information

    Synonyms: 3-(3-Hydroxypropyl)-pyridine 3-(3-Hydroxypropyl)pyridine 3-Pyridinepropanol 3-(pyridin-3-yl)propan-1-ol 3-Propanolpyridine 3-(3-pyridyl)propan-1-ol 3-pyridin-3-ylpropan-1-ol

    Molecular Formula: C8H11NO

    Molecular Weight: 137.18

    MDL Number: MFCD00006414

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    3-(3-Hydroxypropyl)pyridine is an organic compound featuring a pyridine ring substituted with a 3-hydroxypropyl chain. It serves as a versatile heterocyclic building block in organic synthesis, particularly valued for its bifunctional nature combining a basic pyridine nitrogen and a terminal hydroxyl group. Its primary industrial application is as a key intermediate in the synthesis of pharmaceutical compounds. Notably, it is a crucial precursor in the production of certain cardiovascular drugs and other active pharmaceutical ingredients (APIs) where the pyridine moiety and the flexible hydroxyalkyl linker are essential structural components. The compound is also used in the preparation of functional materials and ligands due to its coordination and hydrogen-bonding capabilities. As a bifunctional synthon, it is employed in various coupling reactions, cyclizations, and as a linker in medicinal chemistry for constructing more complex molecular architectures. Standard safety precautions for handling pyridine derivatives and alcohols should be observed.
    Physical Properties

    Boiling Point: 130-133 °C/3 mmHg(lit.)

    Flash Point: 113 °C

    Density: 1.063 g/mL at 25 °C(lit.)

    Refractivity: n20/D 1.53(lit.)

    mg g kg ml l t