Cyclohexanemethanol, 2-amino-, hydrochloride, trans-, CAS No. 28250-45-5

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28250-45-5

Catalog No. EBD2322005

CAS 28250-45-5

Name Cyclohexanemethanol, 2-amino-, hydrochloride, trans-

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Basic Information

Synonyms: Cyclohexanemethanol,2-amino-,hydrochloride,trans- (1R,2R)-2-(hydroxymethyl)cyclohexanaminium cyclohexanemethanol,2-amino-,hydrochloride(1:1),(1R,2R)-rel- trans-2-hydroxymethylcyclohexanaminehydrochloride (trans-2-hydroxymethylcyclohexyl)aminehydrochloride trans-2-hydroxymethylcyclohexylaminemonohydrochloride cyclohexanemethanol,2-amino-,hydrochloride,trans-(8ci) cyclohexanemethanol,2-amino-,hydrochloride,(1r,2r)-rel-(9ci) trans-2-Hydroxymethyl-1-cyclohexylaminehydrochloride

Molecular Formula: C7H16ClNO

Molecular Weight: 165.66

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

Trans-2-(Aminomethyl)cyclohexan-1-ol hydrochloride is a chiral organic compound featuring both an amino group and a hydroxyl group on a cyclohexane ring in a trans configuration. It is commonly supplied as a hydrochloride salt to enhance its stability and handling properties. This compound serves as a valuable chiral building block in pharmaceutical synthesis. Its structure, containing a rigid cyclohexane scaffold with two functional handles (amino and hydroxyl), makes it a versatile intermediate for constructing more complex molecules with defined stereochemistry. It is particularly relevant in the synthesis of active pharmaceutical ingredients (APIs) and other bioactive compounds where the specific spatial arrangement of functional groups is critical for biological activity. As a bifunctional chiral synthon, it is utilized in medicinal chemistry research and process development. The hydrochloride salt form is typically used to facilitate purification and storage.

Physical Properties

Melting Point: 150-155 °C

Boiling Point: 218.8°Cat760mmHg

Flash Point: 86.1°C