1 - Amino - 2 - propanol, CAS No. 2799-16-8

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2799-16-8

Catalog No. EBD4410

CAS 2799-16-8

Name 1 - Amino - 2 - propanol

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Basic Information

Synonyms: (r)-1-amino-2-propanol (r)-(-)-2-hydroxypropylamine (-)-isopropanolamine isopropanolamine (r)-(-)-1-amino-2-propanol,96% (r)-(-)-1-amino-2-propanol,98+% (R)-(-)-1-aminopropan-2-ol (?)-Isopropanolamine (2R)-(-)-1-Amino-2-propanol (2R)-(-)-1-Aminopropan-2-ol (2R)-1-Amino-2-propanol (2R)-1-Aminopropan-2-ol (R)-(-)-Isopropanolamine (R)-(?)-1-Amino-2-propanol 2-Propanol,1-amino-,(R)- (R)-(-)-1-Amino-2-propanol (R)-1-Amino-propan-2-ol 1-amino-2-propanol 2-propanol,1-amino-

Molecular Formula: C3H9NO

Molecular Weight: 7511.0

MDL Number: MFCD00064428

Categories: Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

Product Description:

(R)-(-)-1-Amino-2-propanol is a chiral amino alcohol featuring a primary amine and a secondary hydroxyl group on a three-carbon chain. Its (R)-enantiomer is a key chiral building block in asymmetric synthesis. This compound is primarily utilized as a chiral intermediate in the pharmaceutical industry. It is a critical precursor for the synthesis of various active pharmaceutical ingredients (APIs), including levofloxacin (a fluoroquinolone antibiotic) and other chiral drugs where the stereochemistry is essential for biological activity. Its dual functionality allows for selective derivatization. As a versatile organic synthesis building block, it also serves as a ligand in asymmetric catalysis and a starting material for preparing chiral auxiliaries. The compound is typically a colorless to pale yellow liquid, miscible with water and common organic solvents, and should be handled with standard laboratory safety precautions.

Physical Properties

Melting Point: 24-26 °C(lit.)

Boiling Point: 160 °C(lit.)

Flash Point: 71 °C

Density: 2.6 (vs air)

Solubility: soluble

Refractivity: n20/D 1.448

Storage: 2-8°C

Safety Information

Packing Level: II

Hazard Category: 8

Transport Codes: 3259PSN1

Analytical Data

Appearance: Colorless to light yellow liquid