1,6-Dibromopyrene is an organic compound with the molecular formula C₁₆H₈Br₂. It is a derivative of pyrene, a polycyclic aromatic hydrocarbon (PAH), where two bromine atoms are substituted at the 1 and 6 positions. This compound typically appears as a yellow to orange crystalline solid and is sensitive to light and air. Its primary and most significant application is as a key building block in materials science, particularly in the synthesis of organic semiconductors and optoelectronic materials. The bromine atoms serve as excellent leaving groups in cross-coupling reactions, such as Suzuki, Stille, or Buchwald-Hartwig couplings, enabling the construction of extended π-conjugated systems. These systems are crucial for developing materials used in organic light-emitting diodes (OLEDs), organic field-effect transistors (OFETs), and organic photovoltaic (OPV) cells. Due to its role as a versatile synthetic intermediate, it is also categorized as an organic synthesis building block. It is commercially available for research and development purposes. Standard safety precautions for handling halogenated aromatic compounds should be observed, including the use of personal protective equipment.