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    275826-36-3

    Catalog No. EBD32462

    CAS 275826-36-3

    Name (S)-3-amino-3-(4-bromophenyl)propionic acid

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    Basic Information

    Synonyms: (S)-3-Amino-3-(4-bromo-phenyl)-propionicacid (S)-3-Amino-3-(4-bromophenyl)-propionicacid S-4-Bromophenylalanine (S)-3-Amino-3-(4-bromophenyl)propionicacid (S)-3-amino-3-(4-bromophenyl)propanoicacid

    Molecular Formula: C9H10BrNO2

    Molecular Weight: 244.09

    MDL Number: MFCD03840456

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (S)-3-Amino-3-(4-bromophenyl)propanoic acid is a chiral organic compound featuring a β-amino acid scaffold with a 4-bromophenyl substituent. Its molecular structure combines an aromatic bromine group, a chiral amino group, and a carboxylic acid functionality, making it a versatile building block. This compound is primarily utilized as a key chiral intermediate in pharmaceutical research and development. The presence of the chiral center and the reactive functional groups allows for its incorporation into more complex molecules, particularly in the synthesis of potential drug candidates. The bromophenyl moiety can serve as a handle for further cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling structural diversification. Due to its well-defined structure and functional handles, it is also employed as a specialized organic synthesis building block in medicinal chemistry for constructing peptidomimetics or other bioactive molecules. It is typically handled as a solid and requires storage under appropriate conditions to maintain stability.
    Physical Properties

    Boiling Point: 378.1 °C at 760 mmHg

    Flash Point: 182.5 °C

    Density: 1.585 g/cm3

    Solubility: at 25 deg C (mg/L): 4746

    mg g kg ml l t