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    27489-60-7

    Catalog No. EBD99175

    CAS 27489-60-7

    Name N-(4-hydroxycyclohexyl)acetamide

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    Basic Information

    Synonyms: N-(4-hydroxycyclohexyl)acetamide (E)-4-Acetamidocyclohexanol trans-N-(4-Hydroxycyclohexyl)acetamide

    Molecular Formula: C8H15NO2

    Molecular Weight: 157.21

    MDL Number: MFCD00051422

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Trans-4-Acetamidocyclohexanol is an organic compound featuring a cyclohexane ring substituted with an acetamido group and a hydroxyl group in a trans configuration. It is a white to off-white crystalline powder. This compound is primarily utilized as a key pharmaceutical intermediate. It serves as a crucial building block in the synthesis of various bioactive molecules and active pharmaceutical ingredients (APIs). Its structure, containing both a protected amine (acetamide) and a hydroxyl group, makes it a versatile chiral synthon for constructing more complex molecular architectures, particularly in medicinal chemistry research and development. As an intermediate, it is involved in multi-step synthetic routes. The compound is handled as a fine chemical under standard laboratory conditions, and its use is typically confined to controlled industrial or research settings for further chemical transformation.
    Physical Properties

    Boiling Point: 357.212 °C at 760 mmHg

    Flash Point: 169.836 °C

    Density: 1.077 g/cm3

    mg g kg ml l t