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    273206-92-1

    Catalog No. EBD32345

    CAS 273206-92-1

    Name tert-Butyl rel-(1R,5S,6S)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate

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    Basic Information

    Synonyms: carbamicacid,N-[(1R,5S)-3-azabicyclo[3.1.0]hex-6-yl]-,1,1-dimethylethylester tert-Butyl(1R,5S,6s)-3-azabicyclo[3.1.0]hex-6-ylcarbamate exo-6-amino-3-boc-3-azabicyclo[3.1.0]hexane

    Molecular Formula: C10H18N2O2

    Molecular Weight: 198.26

    MDL Number: MFCD15111971

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    The compound with CAS number 273206-92-1 is known as *tert*-butyl rel-(1R,5s,6s)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate. It is a bicyclic amine derivative featuring a fused aziridine and pyrrolidine ring system, which serves as a conformationally rigid, nitrogen-containing scaffold. The molecule contains both a primary amine and a *tert*-butyl carbamate (Boc) protected secondary amine, making it a versatile chiral building block. This compound is a key synthetic intermediate in medicinal chemistry, particularly for the development of pharmaceutical agents. Its rigid, three-dimensional structure is valuable for constructing molecules that interact with biological targets, such as enzymes or receptors. The presence of multiple nitrogen atoms makes it a privileged scaffold for creating drug candidates with potential activity in areas like central nervous system disorders or infectious diseases. The Boc-protected amine allows for selective deprotection and further functionalization, while the primary amine provides a handle for coupling reactions. Its synthesis and use are primarily documented in patent literature and research publications focused on novel therapeutic compounds, underscoring its role as a specialized intermediate rather than a commodity chemical.
    Physical Properties

    Boiling Point: 305.3°C at 760 mmHg

    Flash Point: 138.5°C

    Density: 1.11g/cm3

    mg g kg ml l t