O-benzyl-hydroxylamine hydrochloride, CAS No. 2687-43-6

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2687-43-6

Catalog No. EBD16812

CAS 2687-43-6

Name O-benzyl-hydroxylamine hydrochloride

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Basic Information

Synonyms: O-benzyl-hydroxylaminehydrochloride O-Benzylhydroxylaminehydrochloride O-BENZYLHYDROXYLAMINECHLORHYDRATE Benzylhydroxylaminehydrochloride [(aminooxy)methyl]benzenehydrochloride(1:1) N-hydroxy-1-phenylmethanaminehydrochloride Benzoxylaminehydrochloride o-benzyl-hydroxylaminhydrochloride labotest-bblt00233131 benzyloxyaminehydrochloride benzyloxyaminehcl benzyloxyamine timtec-bbsbb003971 o-benzylhydroxylammoniumchloride phenylmethoxyaminehydrochloride

Molecular Formula: C7H10ClNO

Molecular Weight: 159.61

MDL Number: MFCD00012952

Categories: Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

O-Benzyl-hydroxylamine hydrochloride is a white to off-white crystalline solid with the molecular formula C7H9NOбдHCl. It is the hydrochloride salt of O-benzylhydroxylamine, featuring a benzyl-protected hydroxylamine group. This compound is widely used as a versatile synthetic building block in organic chemistry, particularly for the introduction of the hydroxylamine moiety into target molecules. Its primary application lies in the synthesis of oximes, hydroxamic acids, and N-alkoxyamines, which are key intermediates in the preparation of pharmaceuticals, agrochemicals, and fine chemicals. In medicinal chemistry, it serves as a crucial fragment for constructing bioactive molecules, including enzyme inhibitors and receptor modulators. The benzyl group acts as a protecting group that can be removed under mild hydrogenolysis conditions, allowing for further functionalization. Additionally, it is employed in the modification of carbonyl compounds and in the synthesis of heterocycles.

Physical Properties

Melting Point: 238 °C (subl.)(lit.)

Boiling Point: 237.5 °C at 760 mmHg

Flash Point: 113.1 °C

Storage: Store at RT.

Analytical Data

Appearance: white to light yellow crystal powder