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    261165-04-2

    Catalog No. EBD2209757

    CAS 261165-04-2

    Name Dicyclohexylamine (S,E)-2-((tert-butoxycarbonyl)amino)-5-phenylpent-4-enoate

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    Basic Information

    Synonyms: Dicyclohexylamine(S,E)-2-((tert-butoxycarbonyl)amino)-5-phenylpent-4-enoate (S)-N-BOC-Styrylalanine (S)-N-tert-Butoxycarbonyl-2-amino-5-phenyl-4-pentenoicacid Boc-L-Styrylalanine-DCHA (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-phenylpent-4-enoate (2S,4E)-2-[(tert-butoxycarbonyl)amino]-5-phenylpent-4-enoicacid Boc-L-Styrylalanine.DCHA

    Molecular Formula: C28H44N2O4

    Molecular Weight: 472.66

    MDL Number: MFCD01860895

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

    Product Description:
    N-Boc-L-phenylalanine dicyclohexylamine salt is a protected amino acid derivative. It consists of L-phenylalanine with its α-amino group protected by a tert-butoxycarbonyl (Boc) group, forming a salt with dicyclohexylamine (DCHA). This salt form enhances the compound's crystallinity and stability, making it easier to handle and purify compared to the free acid form. This compound is a crucial building block in solid-phase peptide synthesis (SPPS) and solution-phase peptide chemistry. The Boc protecting group is stable under basic conditions and can be selectively removed under mild acidic conditions (e.g., using trifluoroacetic acid), allowing for the sequential assembly of peptide chains. L-Phenylalanine is a common hydrophobic amino acid residue found in many biologically active peptides and proteins. Therefore, this Boc-protected salt is widely used in the research and development of peptide-based pharmaceuticals, diagnostic agents, and biochemical tools. The dicyclohexylamine salt offers advantages in purification processes due to its well-defined crystalline properties. It is a standard, high-purity reagent supplied for laboratory and industrial-scale synthesis. Proper handling is required as with all fine chemicals, including the use of personal protective equipment to avoid inhalation or contact.
    Physical Properties

    Boiling Point: 498.1°C at 760 mmHg

    Flash Point: 255.1°C

    Density: 1.15g/cm3

    Storage: Store at -15°C

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