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    26081-07-2

    Catalog No. EBD2301969

    CAS 26081-07-2

    Name 2H-Azepin-2-one,3-aminohexahydro-,hydrochloride

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    Basic Information

    Synonyms: 2H-Azepin-2-one,3-aminohexahydro-,hydrochloride (3S)-3-aminoazepan-2-onehydrochloride 3-Aminohexahydro-2H-azepin-2-onehydrochloride S-3-Aminohexahydro-2H-azepin-2-onehydrochloride (S)-3-Aminohexahydro-2H-Azepin-2-OneMonohydrochlorideLabeledWithCarbon-14

    Molecular Formula: C6H13ClN2O

    Molecular Weight: 164.63

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > APIs and Their Salts > Nervous System Drugs

    Product Description:
    3-Aminohexahydro-2H-azepin-2-one hydrochloride is a heterocyclic organic compound featuring a seven-membered azepane ring with an amide and an amine functional group. It is a white to off-white crystalline powder and is typically supplied as its hydrochloride salt to enhance stability and solubility. This compound serves as a crucial synthetic intermediate in pharmaceutical research and development. Its primary application is in the synthesis of complex molecules targeting the central nervous system. Notably, it is a key building block for the production of besifloxacin, a fourth-generation fluoroquinolone antibiotic used in ophthalmic solutions to treat bacterial conjunctivitis. The molecule's structure, containing both a reactive amine and a constrained lactam ring, makes it a versatile scaffold for constructing pharmacologically active agents, particularly those interacting with neurological targets. As a pharmaceutical intermediate, it is handled under controlled conditions in laboratory and manufacturing settings. Standard safety protocols for handling fine chemicals, including the use of personal protective equipment and adequate ventilation, should be observed. Its synthesis and use are primarily within the domain of advanced medicinal chemistry for creating novel therapeutic entities.
    Physical Properties

    Boiling Point: 340.3 °C at 760 mmHg

    Flash Point: 159.6 °C

    Storage: 2-8°C

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