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    25462-85-5

    Catalog No. EBD43304

    CAS 25462-85-5

    Name 2-Chloro-6-methylpyridine-4-carboxylic acid

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    Basic Information

    Synonyms: 2-Chloro-6-methyl-4-pyridinecarboxylicacid 2-Chloro-6-methylisonicotinicacid 4-Pyridinecarboxylicacid,2-chloro-6-methyl- T6NJBGDVQF1[WLN] 2-Chloro-6-methylpyridine-4-carboxylicacid

    Molecular Formula: C7H6ClNO2

    Molecular Weight: 171.58

    MDL Number: MFCD00052830

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

    Product Description:
    2-Chloro-6-methylpyridine-4-carboxylic acid is a heterocyclic organic compound featuring a pyridine ring substituted with a chloro group at the 2-position, a methyl group at the 6-position, and a carboxylic acid group at the 4-position. It serves as a versatile and important chemical building block in organic synthesis, particularly in the pharmaceutical industry. Its primary application is as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). The presence of multiple reactive sites (carboxylic acid, chloro substituent) allows for diverse derivatization, making it a valuable precursor for constructing complex drug molecules. It is notably used in the development of compounds with potential therapeutic activities. As a bifunctional synthon, it is employed in coupling reactions, amide bond formation, and further functional group transformations. The compound is typically handled as a solid and requires standard laboratory safety precautions for handling carboxylic acids and halogenated compounds.
    Physical Properties

    Melting Point: 208-212 °C (dec.)(lit.)

    Boiling Point: 399 °C at 760 mmHg

    Flash Point: 195.1 °C

    Density: 1.39 g/cm3

    mg g kg ml l t